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Provider Notice issued 11/20/2025

Abrysvo™ (Respiratory Syncytial Virus Vaccine) - Update

Date November 20, 2025
​To Enrolled Physicians, Advanced Practice Nurses, Nurses, Physician Assistants, Local Health Departments, Hospitals, Federally Qualified Health Centers, Rural Health Clinics, Encounter Rate Clinics, Pharmacies
​Re: Abrysvo™ (Respiratory Syncytial Virus Vaccine) - Update

This notice informs providers of updates to the October 14, 2025 provider notice on Respiratory Syncytial Viral (RSV) Season.

Effective November 20, 2025, the Department of Healthcare and Family Services (HFS) is removing the requirements for additional documentation of informed consent beyond the standard methods used for vaccinations and prior authorization for the vaccine Abrysvo, based on the clinical evidence on vaccine safety. The vaccine is now available via medical and pharmacy billing without a prior authorization or submission of additional documentation of weeks of gestation for individuals 19 years of age and older. Those pregnant under the age of 19 are eligible to receive Abrysvo through a Vaccines for Children (VFC) provider. 

Medical providers and pharmacists continue to be responsible for verifying vaccine eligibility, including weeks of gestation for pregnant individuals, and ensuring informed consent.

The Illinois Department of Public Health made the following recommendations in September 2025 regarding RSV vaccination for individuals who have not been previously vaccinated, which align with current CDC recommendations:

  • All pregnant people during weeks 32 through 36 of pregnancy.

  • Adults ages 50 years through 74 years at increased risk of severe RSV disease.  

  • All adults ages 75 years and older.

Information on the Food and Drug Administration’s (FDA) indications for Abrysvo can be found here.

Questions regarding this notice may be directed to the Bureau of Professional and Ancillary Services at 877-782-5565, or the applicable MCO.

 

Laura Phelan, Administrator
Division of Medical Programs